{"product_id":"bionmn","title":"NMN","description":"\u003cp\u003e\u003cb\u003eBioNMN®\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eINTRO\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eAt the core of cellular energy, recovery, and longevity lies one critical molecule: \u003cb\u003eNAD+\u003c\/b\u003e. BioNMN® (Beta-Nicotinamide Mononucleotide) is a direct precursor to NAD+, the essential coenzyme required for ATP production—the fuel that powers nearly every biological process in the body. As NAD+ levels naturally decline with age, cellular efficiency, metabolic resilience, cognitive performance, and mitochondrial function can begin to deteriorate.\u003c\/p\u003e \u003cp\u003eBy supplying a highly bioavailable source of NMN, BioNMN® helps replenish NAD+ levels at the cellular level, supporting sustained energy production, mitochondrial integrity, and whole-body vitality. Designed for optimal absorption, this advanced form of NMN provides a foundational approach to performance, metabolic health, and healthy aging from the inside out.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eFULL SCIENCE\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003cb\u003eBioNMN® (Beta-Nicotinamide Mononucleotide)\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003eNicotinamide Mononucleotide (NMN) is a ribo-nucleotide, which is a simple structural unit of RNA. NMN is the direct precursor of nicotinamide adenine dinucleotide (NAD+) and is considered a vital component to cellular increases in NAD+ levels. NAD+ is an essential coenzyme required to produce ATP (adenosine triphosphate), the fuel used by almost all cells in the body. As we age, NAD+ levels naturally decline, which can lead to less-than-optimal functioning and contribute to conditions such as obesity, insulin resistance, and impaired cognitive function.\u003c\/p\u003e \u003cp\u003eWhile humans cannot absorb NAD directly, using NAD+ precursors like NMN can help maintain NAD+ levels. BioNMN® emphasizes enhanced bioavailability so the full benefits of this ingredient can be achieved.\u003c\/p\u003e \u003cp\u003eNMN supplementation offers a wide range of benefits that influence nearly all body systems, including brain and cardiovascular support, reduced age-related inflammation, neuroprotection, hormonal balance, improved mitochondrial function, enhanced muscle endurance and strength, and overall longevity. These benefits rely on NAD+ as a key coenzyme that drives these biological processes.\u003c\/p\u003e \u003cp\u003eIn terms of muscle performance, skeletal muscles require significant amounts of energy molecules to maintain strength and function. NAD+ is required to metabolize these molecules, meaning muscles benefit from a steady supply of NMN as a building block.\u003c\/p\u003e \u003cp\u003eMitochondria, known as the powerhouse of the cell, are essential for converting nutrients into usable energy. NAD+ plays a central role in this metabolic process. Without sufficient NAD+, mitochondria cannot function properly, leading to reduced energy production and potential cellular damage. Research suggests that NMN supplementation supports NAD+ production, helping protect mitochondria and maintain proper metabolic function.\u003c\/p\u003e \u003cp\u003eNMN also plays a role in longevity. As many bodily functions decline with age, maintaining NAD+ levels may help slow aspects of the aging process. Supporting NAD+ levels may help sustain optimal function across body systems over time, while low levels are linked to increased risk of dysfunction and disease.\u003c\/p\u003e \u003cp\u003e\u003cb\u003eREFERENCES\u003c\/b\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eNomiyama T, Setoyama D, Yasukawa T, Kang D. Mitochondria Metabolomics Reveals a Role of β-Nicotinamide Mononucleotide Metabolism in Mitochondrial DNA Replication. J Biochem. 2021.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eKlimova N., Long A., Kristian T. (2019). Nicotinamide mononucleotide alters mitochondrial dynamics by SIRT3-dependent mechanism in male mice.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eShade C. (2020). The Science Behind NMN—A Stable, Reliable NAD+ Activator and Anti-Aging Molecule.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eYoshino J., Baur J.A., Imai S. (2018). NAD+ Intermediates: The Biology and Therapeutic Potential of NMN and NR.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eImai S., Guarente L. (2014). NAD+ and sirtuins in aging and disease.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eCanto C., Menzies K.J., Auwerx J. (2015). NAD+ Metabolism and the Control of Energy Homeostasis.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eMills K.F., et al. (2016). Long-Term Administration of NMN Mitigates Age-Associated Physiological Decline in Mice.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eGomes A.P., et al. (2013). Declining NAD+ Disrupts Cellular Communication during Aging.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eYoshino J., et al. (2021). NMN increases muscle insulin sensitivity in prediabetic women.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eVerdin E. (2015). NAD+ in aging, metabolism, and neurodegeneration.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eRajman L., Chwalek K., Sinclair D.A. (2018). Therapeutic Potential of NAD-Boosting Molecules.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eLiao B., et al. (2021). NMN supplementation enhances aerobic capacity in amateur runners.\u003c\/i\u003e\u003c\/p\u003e \u003cp\u003e\u003ci\u003eSource: :contentReference[oaicite:0]{index=0}\u003c\/i\u003e\u003c\/p\u003e","brand":"Core Nutritionals","offers":[{"title":"Default Title","offer_id":45034516021424,"sku":"850080302644","price":24.99,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/2440\/0931\/files\/NMN_FRONT_674013b3-539b-45f5-b123-47fdd43e6720.png?v=1775484886","url":"https:\/\/www.corenutritionals.com\/products\/bionmn","provider":"Core Nutritionals","version":"1.0","type":"link"}